Build the genome. Spend the ATP. Survive the siege.
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Adenosine triphosphate (ATP) is the energy currency of every living cell on Earth. When your muscles move, when neurons fire, when DNA is copied — ATP pays the bill. In ATP Siege, every action your microbe takes costs real ATP, calculated from actual biochemistry.
Every gene in this game is a real gene — fliC builds a real flagellum, cas3 is a real CRISPR defense system, hlyA is a real toxin. ATP costs come from published biochemistry literature. You learn biology by playing, not by reading a textbook.
You guide a microbial colony. Pick starting genes, gather DNA from the environment, survive viral attacks, evolve new capabilities. Eventually — if your colony earns it — achieve endosymbiosis and gain a mitochondrion. Then the real game begins.
Start with a gene bundle — Swimmer, Scavenger, or Crawler. Each is based on real prokaryotic biology.
Each gene expresses a real protein. Proteins enable real functions — movement, defense, nutrient uptake, division.
Every action costs ATP. Run out and your colony starves. Real oxidative phosphorylation math governs your energy budget.
Pick up DNA from the environment. Survive viruses. Mutate. Combine genes for emergent capabilities — real emergence, real biology.
Builds the helical filament of the bacterial flagellum. FliC monomers polymerize into a rotating propeller that drives swimming at up to 30 body-lengths per second — equivalent to a human sprinting at 200 km/h.
Source: NCBI Gene ID 945702 · UniProt P04949
ATP Siege is designed to make microbiology, genetics, and evolutionary biology visceral and memorable. Students don't read about horizontal gene transfer — they watch a plasmid jump between colonies and change the outcome of their game.